Premium quality “made in Germany”, excellent safety, and proven efficacy are our highest values.
Our core competence is the production of Ectoin®, Glycoin® natural, and Hydroxyectoin. Since our founding in 1993, the know-how, experience and passion of our staff have nurtured us to what bitop is today: an expert in the biotechnological manufacturing of extremolytes. We develop and manufacture solely at our own production facility in Witten assuring premium quality “made in Germany” for our worldwide customers.
The design, development, manufacturing, and distribution of our Ectoin®-containing medical devices are subject to a certified quality management system according to DIN EN ISO 13485, fully monitored by us. bitop meets the requirements of 93/42/EWG (Notified Body: TÜV Rheinland LGA Products GmbH). Our finished medical devices are manufactured by experienced and qualified contract manufacturers in Germany, Spain, and France according to ISO and/or GMP Standards.
The quality of our extremolytes and finished products is mainly characterized by their safety and scientifically proven efficacy. Together with academic partners, we have performed numerous preclinical trials to prove the safety of our extremolytes and to understand their mode of action. Moreover, we have been continuously conducting clinical investigations with our finished products in independent study centers to substantiate their claims with facts. Up to now, we have conducted more than 20 clinical studies including more than 1.200 patients in different indications. Corresponding studies of partners and customers are not included. Please contact us for more detailed information about clinical studies.
Please contact us for more detailed information about clinical studies.